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473 * Wed, 8/1/2012, 8:30 AM - 10:20 AM CC-Room 23A
Innovations in Survival Analysis: PFS and Other Issues — Contributed Papers
Biopharmaceutical Section
Chair(s): Steven Sun, Johnson & Johnson
8:35 AM On the Translation of a Treatment's Effect on Disease Progression Into an Effect on Overall Survival Qi Jiang, Amgen, Inc. ; Steven Michael Snapinn, Amgen, Inc.
8:50 AM Translation of Progression-Free Survival Benefit Into Overall Survival in Cancer Trials Yiyun Tang, Pfizer Inc. ; Keiji Imai, Pfizer Inc. ; Paul Bycott, Pfizer Inc.
9:05 AM Estimation of Correlation Between Overall Survival and Surrogate Endpoints — Fang Fang, Bayer Healthcare Pharmaceuticals ; Liping Huang, Bayer Healthcare Pharmaceuticals ; Minghua Shan, Bayer Healthcare Pharmaceuticals ; Xiaosha Zhang, Astellas Pharma U.S., Inc.
9:20 AM Audit Strategies for Progressive-Free Survival Meihua Wu, University of Michigan ; Kalyanee Kalyanee Appann, Novartis ; William Mietlowski, Novartis ; Yong Zhang, Novartis ; Can Cai, Novartis ; Paramita Saha, Novartis
9:35 AM A Bayesian Approach in Assessing Surrogacy of Clinical Trial Endpoints Manuela Buzoianu, PhD, FDA ; Shengyan Hong, MedImmune
9:50 AM Semi-Mechanistic Modeling of the Dependence Structure Between Progression-Free Survival and Overall Survival Dominik Heinzmann, Roche
10:05 AM Competing Risk Analysis of PFS Considering Patients Who Switch Therapy Prior to Progression Lixia Jiao, Sanofi Aventis



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