JSM 2012 Online Program

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246 *	Mon, 7/30/2012, 2:00 PM - 3:50 PM	CC-Room 23A
PK and QTc Analysis — Contributed Papers
Biopharmaceutical Section
Chair(s): Jaya Natarajan, Janssen Pharmaceuticals R&D
2:05 PM	Minimum-Chi-Square-Estimation of Pharmacokinetic Parameters — Karl-Ernst Biebler, Ernst-Moritz-Arndt University
2:20 PM	On the Calculation of Terminal Phase Half-life and Missing Not At Random — Shu Zhang, Eisai, Inc.
2:35 PM	Dose Proportionality Assessment Under Differing Alternating Panel Designs — Deborah Panebianco, Merck ; Akira Wakana, MSD KK
2:50 PM	A New Approach to Evaluate the Drug Effect on the QTc Interval in Thorough QT/QTc Study — Shui He
3:05 PM	Inappropriate Covariance Structure May Lead to Smaller Spurious Variance Estimation of Drug Effect in TQT Crossover Study — Li Fan, Merck ; Xiaodong Li, Merck
3:20 PM	An Investigation of Effect of Baseline Definition in Parallel Nested Crossover Studies — Hui Zhi, GlaxoSmithKline ; Gary Koch, The University of North Carolina at Chapel Hill
3:35 PM	Floor Discussion

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