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Activity Number: 550
Type: Invited
Date/Time: Wednesday, August 1, 2012 : 2:00 PM to 3:50 PM
Sponsor: Memorial
Abstract - #306929
Title: Memories of Working on Clinical Trials with Paul Meier
Author(s): David DeMets*+
Companies: University of Wisconsin-Madison
Address: , , ,
Keywords:
Abstract:

Most biostatisticians are familiar with the Kaplan-Meier estimator for censored survival data and the wide spread use of that methodology for the analysis of clinical trials. However, Paul Meier's contributions to clinical trials goes far beyond this statistical method. He was one of the founders of the Society for Clinical Trials and an active participant in that society's annual meeting throughout his career. Beginning with the Salk polio vaccine trial, Paul was active in the design, monitoring and analysis of clinical trials as a member of either a trial steering committee or the data monitoring committee or perhaps as a critic. He was a strong advocate for the randomized clinical trial. During my own career, I had the privilege of working with Paul on a number of trials, including my first clinical trial experience through the Urokinase Streptokinase Pulmonary Embolism Trial. Experiences and lessons learned from Paul during my career will be shared.


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