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Abstract Details

Activity Number: 521
Type: Contributed
Date/Time: Wednesday, August 1, 2012 : 10:30 AM to 12:20 PM
Sponsor: Section on Survey Research Methods
Abstract - #306685
Title: Concurrent Criterion-Related Validity of a Multidimensional Model of Symptoms of Depression in Organ Transplant Recipients
Author(s): Irene Feurer*+ and Leigh Anne D Redhage
Companies: Vanderbilt University Medical Center and Vanderbilt University Medical Center
Address: 1346 Otter Creek Road, Nashville, TN, 37215-5213, United States
Keywords: survey scaling ; depression ; organ transplantation ; quality of life ; latent variable models

Purpose: To evaluate a condition-specific approach to scoring a depression survey. Methods: 1,340 organ transplant recipients completed the Center for Epidemiologic Studies Depression (CES-D) Scale, SF-36 Health Survey (SF-36), EuroQoL (EQ-5D) and Beck Anxiety Inventory (BAI). Data were analyzed using latent variable methods and multivariable linear regression. Results: Three CES-D subscales were identified: somatic symptoms (SOM), isolation (ISO) and positive affect (PA). Multivariable models of CES-D subscale scores included the SF-36 physical and mental scales, EQ-5D valuations, and BAI subscales. Higher (worse) SOM scores were associated with lower (worse) physical and mental SF-36, lower (worse) EQ-5D, and higher (worse) BAI neurophysiologic, subjective and autonomic scores. Higher (worse) ISO scores were associated with higher physical and lower mental SF-36, lower EQ-5D, better BAI neurophysiologic and worse BAI subjective scores. Higher (better) PA scores were associated with better SF-36 physical and mental scores, and worse BAI neurophysiologic and autonomic scores. Conclusion: A multidimensional scoring system for CES-D item data is applicable for transplant recipients.

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