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Activity Number: 411
Type: Contributed
Date/Time: Tuesday, July 31, 2012 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #306381
Title: Estimating Exposure-Response Relationships in Case-Control Studies
Author(s): Catherine Mary Crespi*+ and Leeka Kheifets and Marco Vinceti
Companies: University of California at Los Angeles and University of California at Los Angeles and University of Modena and Reggio Emilia
Address: Room A2-125 CHS Box 951772, Los Angeles, CA, 90095,
Keywords: exposure-response ; magnetic field exposure ; childhood cancer ; case-control study

Many epidemiological exposure variables have right-skewed distributions with sparse data at high exposure levels. Visualizing and estimating exposure-response relationships is further challenging for case-control studies, as the dependent variable is binary. We present improved approaches for estimating the exposure-response relation in such settings. Data from case-control studies of childhood cancer are used to illustrate the methods.

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