JSM 2012 Home

JSM 2012 Online Program

The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.

Online Program Home

Abstract Details

Activity Number: 58
Type: Topic Contributed
Date/Time: Sunday, July 29, 2012 : 4:00 PM to 5:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #306221
Title: Incorporating Clinical Perspectives Into the Design of Adaptive Clinical Trials: Process and Impact
Author(s): Roger Lewis*+
Companies: Los Angeles Biomedical Research Institute
Address: Dept of Emergency Medicine, Torrance, CA, 90502-2004, United States
Keywords: Adaptive Clinical Trials ; Clinical Trial Design

One of the advantages of adaptive clinical trials is the ability to flexibly and carefully tailor the trial characteristics to meet the scientific and clinical goals of key stakeholders. Since an important goal of late phase clinical trials is to influence the clinical practice patterns of clinicians, when the results indicate it is appropriate to do so, it is useful to consider the perspectives of clinicians when designing late phase adaptive clinical trials. The speaker, who is a clinician actively involved in the design, implementation, and oversight of adaptive clinical trials, will describe the opportunities and challenges associated with incorporating clinicians into the trial design process. Experience gained from recent work with clinical investigators from a large, federally-funded clinical trials network will be used to illustrate effective methods for incorporating clinical persectives into the adaptive clinical trial design process. An effective partnership between statisticians and clinicians will result in a clinical trial that is most likely to successfully answer key clinical questions and positively influence clinical care.

The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2012 program

2012 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.