JSM 2012 Home

JSM 2012 Online Program

The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.

Online Program Home

Abstract Details

Activity Number: 507
Type: Contributed
Date/Time: Wednesday, August 1, 2012 : 10:30 AM to 12:20 PM
Sponsor: Section on Statistical Consulting
Abstract - #305779
Title: Methods for Classifying Changes in Bacterial Prevalence Over Time
Author(s): Raymond G Hoffmann*+ and Thomas J Hoffmann and Sandra McLellan and Jessica VandeWalle and Pippa Simpson
Companies: Medical College of Wisconsin and University of California at San Francisco and University of Wisconsin-Milwaukee and University of Wisconsin-Milwaukee and Medical College of Wisconsin
Address: Quantitative Health Sciences, Pediatrics, Milwaukee, WI, 53226-0509, United States
Keywords: genetics ; time series modeling ; wavelets ; irregular sampling points ; cluster analysis

Information about the prevalence of bacterial taxa in water samples can be determined via next generation sequencing. Samples were taken from two different, but related, sites in Lake Michigan over a three year period. After aggregation of similar taxa there were 22 time series of bacterial prevalence x two sites. The goal was to identify the taxa that had similar temporal patterns. Wavelet analysis after filtering to reduce sampling noise was used to determine the temporal characteristics of each of the time series because of the irregular time measurements and the jagged shape of the prevalence curve. Comparisons of clustering of the wavelet coefficients, the coefficients of a harmonic regression model and classification and regression tree (CART) analysis with Random Forests are made to identify the stability and utility of the classifications across different cluster thresholds.

The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2012 program

2012 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.