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Abstract Details
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Activity Number:
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231
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Type:
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Topic Contributed
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Date/Time:
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Monday, July 30, 2012 : 2:00 PM to 3:50 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #305431 |
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Title:
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Bayesian Adaptive Phase II Trial with a Nonmonotonic Dose-Response Curve
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Author(s):
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Yuyan Duan*+ and Robert Noble
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Companies:
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and Aptiv Solutions
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Address:
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8 Hutchinson Rd., Winchester, MA, 01890, United States
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Keywords:
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adaptive design ;
bayesian rule ;
phase II trial
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Abstract:
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A case study of a Phase II Bayesian adaptive design will be presented and issues will be discussed. Characteristics of this binary endpoint study include: (1) combination of proof of concept and dose-finding, and (2) potential for the dose-response curve to have a reflection point.
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Authors who are presenting talks have a * after their name.
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