JSM 2012 Home

JSM 2012 Online Program

The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.

Online Program Home

Abstract Details

Activity Number: 503
Type: Topic Contributed
Date/Time: Wednesday, August 1, 2012 : 10:30 AM to 12:20 PM
Sponsor: Health Policy Statistics Section
Abstract - #305211
Title: Scoring Systems for Person-Reported Outcome Measurements
Author(s): Laura Lee Johnson*+ and Steven D. Edland, Ph.D*+ and M.Colin Ard, Ph.D*+ and Lisa A. Kammerman, Ph.D*+
Companies: FDA/CDER and National Center for Complementary and Alternative Medicine and University of California at San Diego
Address: National Institutes of Health, Bethesda, MD, 20892, Department of Family Preventive Medicine, La Jolla, CA, 92093, Department of Neuroscience, La Jolla, CA, 92093, , , ,
Keywords: patient reported outcomes ; item response theory ; latent models ; Alzheimer's disease

Patient, Clinician, and Observer Reported Outcomes all require intensive and structured development. However, for some instruments complicated preliminary work is left behind when scoring systems are devised and implemented. Frequently, responses for distinct items or the number of symptoms are simply added together to compute a total score. Such a practice ignores the potential associations among the individual items and symptoms. Several modern statistical methods employ a variety of techniques to develop scoring systems, including latent variable modeling approaches for rescoring functional outcome measures, will be discussed by the panelists. In recent work a group demonstrated empirically with prior trial data that rescoring can improve the efficiency of clinical trials by at least 15 percent. The panel also will consider the expected report from PCORI (Patient Centered Outcomes Research Institute) on methodological standards for conducting patient-centered outcomes research.

The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2012 program

2012 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.