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Abstract Details

Activity Number: 58
Type: Topic Contributed
Date/Time: Sunday, July 29, 2012 : 4:00 PM to 5:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #305151
Title: Dynamic Comparison of Simulated Adaptive Trials
Author(s): Russell Wolfinger*+ and Richard Zink and Walter Boyle
Companies: SAS Institute and SAS Institute and SAS Institute
Address: DNA-Analytical Solutions, Cary, NC, 27513, United States
Keywords: adaptive trials ; mixed model ; visual analytics ; trial simulation
Abstract:

We present a visual analytic approach to exploring and comparing results from simulated trials. The interply between statistics and graphics helps elucidate important findings from the simulations and sharpen signals amidst noise. A mixed model repeated measures (MMRM) analysis of candidate frequentist and Bayesian adaptive trials provides illustration.


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