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Abstract Details
Activity Number:
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58
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Type:
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Topic Contributed
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Date/Time:
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Sunday, July 29, 2012 : 4:00 PM to 5:50 PM
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Sponsor:
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Biopharmaceutical Section
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Abstract - #305151 |
Title:
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Dynamic Comparison of Simulated Adaptive Trials
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Author(s):
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Russell Wolfinger*+ and Richard Zink and Walter Boyle
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Companies:
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SAS Institute and SAS Institute and SAS Institute
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Address:
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DNA-Analytical Solutions, Cary, NC, 27513, United States
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Keywords:
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adaptive trials ;
mixed model ;
visual analytics ;
trial simulation
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Abstract:
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We present a visual analytic approach to exploring and comparing results from simulated trials. The interply between statistics and graphics helps elucidate important findings from the simulations and sharpen signals amidst noise. A mixed model repeated measures (MMRM) analysis of candidate frequentist and Bayesian adaptive trials provides illustration.
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