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Abstract Details
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Activity Number:
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34
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Type:
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Contributed
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Date/Time:
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Sunday, July 29, 2012 : 2:00 PM to 3:50 PM
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Sponsor:
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Biometrics Section
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| Abstract - #304938 |
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Title:
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Power and stability properties of resampling-based multiple testing procedures with applications to gene oncology studies
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Author(s):
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Dongmei Li*+ and Gang Han
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Companies:
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University of Hawaii at Manoa and Moffitt Cancer Center
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Address:
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2640 Dole Street, Honolulu, HI, 96822-2342, United States
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Keywords:
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Resampling ;
multiple testing procedures ;
Power ;
Stability
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Abstract:
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Resampling-based multiple testing procedures are widely used in genomic studies to identify differentially expressed genes and to conduct genome-wised association studies (GWAS). However, the power and stability properties of these popular resampling-based multiple testing procedures have not been extensively evaluated yet. Our study focus on investigating the power and stability of several resampling-based multiple testing procedures frequently used in microarray studies through simulations and gene oncology examples and provide some guidance and cautions for researchers using those methods in microarray data analysis.
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