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Abstract Details
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Activity Number:
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624
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Type:
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Contributed
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Date/Time:
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Thursday, August 2, 2012 : 8:30 AM to 10:20 AM
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Sponsor:
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Section on Statistics in Epidemiology
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| Abstract - #304342 |
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Title:
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Estimation of the Common Risk Difference in Stratified Paired Binary Data with Homogeneous Stratum Effect
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Author(s):
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Yan Zhao*+ and Dewi Gabriela Rahardja
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Companies:
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Oklahoma University Health Sciences Center and FDA
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Address:
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4502 East 41st Street, Tulsa, OK, 74135, United States
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Keywords:
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Cochran-Manten-Hanszel test ;
common risk difference ;
McNemar's test ;
paired binary data ;
stratified data
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Abstract:
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The McNemar's test is commonly used to test for the risk difference between two binary variables on matched pairs. For stratified paired binary data, recently a test for testing homogeneous stratum effect (HSE) has been developed. If HSE is rejected, then the McNemar's test should be applied by stratum; otherwise, in this paper we propose a concept of common risk difference (CRD) across the strata and derive point estimators and confidence intervals for CRD. We use a cancer study for illustration and conduct simulations to recommend point estimators and associated confidence intervals with good statistical property.
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