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Abstract Details

Activity Number: 572
Type: Contributed
Date/Time: Wednesday, August 1, 2012 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #304160
Title: A Bayesian Secondary Analysis in an Asthma Study
Author(s): Samuel P. Wilcock*+ and Vernon M. Chinchilli
Companies: Messiah College and Penn State Hershey College of Medicine
Address: 1 College Ave, Grantham, PA, 17027, United States
Keywords: Clinical Trials ; Cross-over Design ; Non-inferiority Studies ; Bayesian Analysis ; Mixed Models ; Asthma Treatment

A recent study published in the New England Journal of Medicine by the Asthma Clinical Research Network (ACRN) compared three different treatments for their effectiveness in treating adults with uncontrolled asthma. This paper will describe the study design and its results, then detail the beginnings of a secondary analysis using Bayesian methods to estimate the parameters of interest. The methods will be explained, and the preliminary estimates given and contextualized. The paper will conclude with a discussion of the next steps and the goals for further analysis of the data in this study.

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