The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.
Online Program Home
Abstract Details
|
Activity Number:
|
586
|
|
Type:
|
Invited
|
|
Date/Time:
|
Thursday, August 2, 2012 : 8:30 AM to 10:20 AM
|
|
Sponsor:
|
ENAR
|
| Abstract - #303914 |
|
Title:
|
Equivalence Evaluation Between Xenografts and Primary Tumors
|
|
Author(s):
|
Xiangqin Cui*+ and Zhijin Wu
|
|
Companies:
|
The University of Alabama at Birmingham and Brown University
|
|
Address:
|
Department of Biostatistics, Birmingham, AL, ,
|
|
Keywords:
|
equivalence ;
xenografts ;
tumor ;
genome ;
transcriptome
|
|
Abstract:
|
Xenografts established in mice from patient tumors are promising models for study patient-specific tumorigenesis and drug testing, which is often prohibitive in patients. However, before xenografts can be used as a surrogate, the characteristics of the xenografts need to be thoroughly evaluated at every possible level to establish equivalence with the primary tumor. I will describe our effort in evaluating the equivalence between xenografts and primary tumors using brain tumor as an example based on the large amount of genomic and transcriptomic data in The Cancer Genome Atlas (TCGA) database together with some other public and private xenograft data.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2012 program
|
2012 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.