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Abstract Details
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Activity Number:
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218
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Type:
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Invited
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Date/Time:
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Monday, July 30, 2012 : 2:00 PM to 3:50 PM
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Sponsor:
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WNAR
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| Abstract - #303501 |
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Title:
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Nonparametric Tests for the Frailty Distribution in Proportional Hazards Models with Shared Frailty
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Author(s):
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Gerda Claeskens*+
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Companies:
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K. U. Leuven
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Address:
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Naamsestraat 69, Leuven, International, 3000, Belgium
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Keywords:
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frailty distribution ;
series expansion ;
nonparametric test ;
random effect
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Abstract:
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Testing for observable structures (such as the shape of a mean function) has been well studied. In this talk tests for more indirect quantities will be discussed. Correlated survival data are often modeled via proportional hazards models with a shared frailty. A common assumption is that the frailty distribution is gamma. We construct tests for the null hypothesis of a gamma frailty distribution that are nonparametric in spirit and that are in the style of the order selection tests for the normality of the random effects in linear mixed models, using ideas of flexible modeling of random effects by series expansions. A new class of frailty models is constructed that extend the gamma frailty model by using certain polynomial expansions that are orthogonal with respect to the gamma density. Simulations and data examples illustrate the test's performance.
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Authors who are presenting talks have a * after their name.
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