JSM 2011 Online Program

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Abstract Details

Activity Number: 617
Type: Contributed
Date/Time: Thursday, August 4, 2011 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #302604
Title: The Per Family Error Rate of a Stepwise Multiple Testing Procedure
Author(s): Alexander Y. Gordon*+
Companies: The University of North Carolina at Charlotte
Address: 9201 University City Blvd, Charlotte, NC, 28223,
Keywords: multiple testing procedure ; per family error rate ; expected number of false rejections ; step-up procedure ; step-down procedure ; step-up-down procedure
Abstract:

The per family error rate (PFER) of a multiple testing procedure (MTP) introduced by Tukey (1953) is the expected number of false rejections. We are interested in the exact level at which a given MTP controls the PFER, no restrictions being imposed on the underlying joint distribution of the p-values associated with the hypotheses being tested. Let M be a procedure that belongs to one of the two most popular classes - those of step-down (Holm type) or step-up (Benjamini-Hochberg type) MTPs, or more generally to the class of step-up-down procedures introduced by Tamhane, Liu and Dunnett (1998). We present explicit formulas that express the exact level at which the procedure M controls the PFER in terms of the critical values of M.


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