JSM 2011 Online Program

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Abstract Details

Activity Number: 220
Type: Topic Contributed
Date/Time: Monday, August 1, 2011 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistical Consulting
Abstract - #302485
Title: Annotation: Biological Meaning from Statistical Genomics
Author(s): David Rocke*+
Companies: University of California at Davis
Address: Division of Biostatistics, Davis, CA, 95616,
Keywords: consulting ; annotation ; genomics ; biology
Abstract:

The result of the statistical analysis of gene expression data, proteomics data, or metabolomics data is often a list of gene, proteins, or metabolites that differ significantly. These lists can be difficult for biologists to interpret, and are insufficient for publication of results in major journals. There are now many tools that can be used to explore the biological properties of lists of molecules, and for effective collaboration, statisticians need to be able to use these tools and to understand the results biologically and statistically. In this presentation, I discuss several of these tools and how to use them most effectively in statistical consulting. Illustrations are drawn from radiation biology and cancer therapy.


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