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Abstract Details
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Activity Number:
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611
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 4, 2011 : 8:30 AM to 10:20 AM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #302023 |
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Title:
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Bayesian Approaches to Subgroup Meta-Analysis
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Author(s):
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Lurdes Y. T. Inoue*+
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Companies:
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University of Washington
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Address:
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F600 Health Sciences Building - Box 357232, Seattle, WA, 98195,
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Keywords:
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Bayesian methods ;
meta-analysis ;
ICD trials ;
effectiveness ;
sudden cardiac death
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Abstract:
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Sudden cardiac death (SCD), usually due to a ventricular tachyarrhythmia, is one the most common causes of death in the United States. Recent clinical trials have shown that the implantable cardioverter defibrillator (ICD) reduces the risk of SCD in certain patient populations. Given the substantial cost associated with ICD implantation and followup, the clinical and policy community currently seek to better understand effectiveness of ICDs in the overall patient population as well as in subgroups. In this talk we discuss Bayesian approaches to investigate whether cumulative data from eight ICD trials provide evidence of treatment effect on mortality in the overall patient population and in the subgroups of interest.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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