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Abstract Details
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Activity Number:
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611
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Type:
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Topic Contributed
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Date/Time:
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Thursday, August 4, 2011 : 8:30 AM to 10:20 AM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #302007 |
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Title:
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Bayesian Borrowing in Device Trials
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Author(s):
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Kert Viele*+ and Scott Berry
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Companies:
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Berry Consultants and Berry Consultants
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Address:
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1024 Park Place Drive, Richmond, KY, 40475,
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Keywords:
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Medical Devices ;
Hierarchical Modeling ;
Borrowing
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Abstract:
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We will compare several different features of Bayesian borrowing of information in device trials, including the incorporation of historical data and the borrowing of information within a single trial through hierarchical modeling. We will compare and contrast these Bayesian methods to frequentist counterparts and include the effect of these Bayesian methods on the frequentist properties (type I error and power) on the resulting trial designs.
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