The views expressed here are those of the individual authors and not necessarily those of the JSM sponsors, their officers, or their staff.
Abstract Details
|
Activity Number:
|
565
|
|
Type:
|
Topic Contributed
|
|
Date/Time:
|
Wednesday, August 3, 2011 : 2:00 PM to 3:50 PM
|
|
Sponsor:
|
Biopharmaceutical Section
|
| Abstract - #301421 |
|
Title:
|
A Sensitivity Analysis of Repeat Revascularization Causal Effect on Mortality and Morbidity in Drug Eluting Stent Clinical Trials
|
|
Author(s):
|
Jian Huang*+
|
|
Companies:
|
Boston Scientific Corporation
|
|
Address:
|
4100 Hamline Avenue North, St. Paul, MN, 55112,
|
|
Keywords:
|
Causal effect ;
Sensitive analysis ;
Bias
|
|
Abstract:
|
In drug eluting stent clinical trials, Repeat Revascularization is often defined as an important safety outcome. However the revascularization procedure itself is cosidered a treatment. The usual approach for the estimation of treatment effect on mortality and morbidity may be biased, especially when many patients receive repeat revascularization due to disease progression after randomized for the original revascularization treatment. In this presentation, the different statistical methods on how to address the causal effect as well as real-life examples will be provided.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2011 program
|
2011 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.