JSM 2011 Online Program

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Abstract Details

Activity Number: 222
Type: Topic Contributed
Date/Time: Monday, August 1, 2011 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistical Education
Abstract - #301017
Title: Statistics and Causation: Past, Present, and Future
Author(s): Herbert Weisberg*+
Companies: Correlation Research, Inc.
Address: 61 Pheasant Landing, Needham, MA, 02492,
Keywords: Clinical trials ; history of medicine ; potential outcomes ; individualized treatment effects ; personalized medicine ; causal models

The rationale for large-scale randomized clinical trials so predominates today that essential limitations of this gold standard are rarely considered. However, this attitude is quite recent and in sharp contrast with earlier notions about the nature of clinical research. Acceptance of human experimentation in its current form came about largely because of particular conditions that pertained shortly after World War II. Although current circumstances have changed, the basic methodology of clinical trials has remained essentially constant. However, new realities imply the need to reconsider the ways in which these studies should be designed and analyzed in the future.

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