JSM 2011 Online Program

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Abstract Details

Activity Number: 510
Type: Contributed
Date/Time: Wednesday, August 3, 2011 : 10:30 AM to 12:20 PM
Sponsor: Section on Nonparametric Statistics
Abstract - #300897
Title: Semiparametric Estimation for Mean Response with Nonresponse Data
Author(s): Zonghui Hu*+
Companies: National Institute of Allergy and Infectious Diseases
Address: 6700 Rockledge, Bethesda, MD, 20817, USA
Keywords: propensity score ; inverse propensity weighting ; mixed-effects modelling ; robust estimation

We study the effect of continuous versus intermittent antiretroviral therapy on CD4 responses in HIV infected patients undergoing IL-2 cycle. Each patient in the study goes through multiple switches between continuous and intermittent IL-2 cycles, where switches are not randomized but depend on the patient's disease status. We propose a causal estimation of the treatment effect, which takes into account the repeated observations within each patient.

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