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Abstract Details
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Activity Number:
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216
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Type:
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Invited
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Date/Time:
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Monday, August 1, 2011 : 2:00 PM to 3:50 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #300411 |
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Title:
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New Methodologies and Examples for Confirmatory Adaptive Designs
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Author(s):
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Werner Brannath*+
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Companies:
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University of Bremen
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Address:
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Achterstr. 30, Bremen, 28359, Germany
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Keywords:
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adaptive design ;
flexible design ;
treatment selection ;
multiple type I error rate ;
response adaptive allocation
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Abstract:
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The talk will give an introduction to recently developed statistical methodologies for confirmatory adaptive designs.Such designs involve features like sample size re-estimation, treatment or subgroup selection at an interim analysis. One new topic will be a statistical methodolgy to control type I error rates in two-stage designs with response adaptive treatment allocation in the first part at which end treamtents are selected, and a second stage where the selected treatments are further investigated in a classical parallel group design.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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