JSM 2011 Online Program

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Abstract Details

Activity Number: 598
Type: Invited
Date/Time: Thursday, August 4, 2011 : 8:30 AM to 10:20 AM
Sponsor: SSC
Abstract - #300372
Title: Semiparametric Regression with Interval-Censored Data
Author(s): Audrey Boruvka*+ and Richard J. Cook
Companies: University of Waterloo and University of Waterloo
Address: Department of Statistics and Actuarial Science, Waterloo, ON, N2L 3G1, Canada
Keywords: intensity-based regression model ; interval censoring ; semiparametric maximum likelihood
Abstract:

Event history data are often observed at discrete inspection times, leading to interval censoring. We examine the extension of semiparametric maximum likelihood for interval-censored survival data to Cox model alternatives, panel observation schemes and multiple event types. Standard computational methods can prove unwieldy in these more general problem settings. To address this issue we consider the adaptation of dimension-reduction strategies recently considered for nonparametric survival data. Numerical performance and application of our proposed methods are demonstrated using some simple event history models. We conclude with a discussion on how these results can be used to deal with other forms of incomplete data.


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