JSM 2011 Online Program

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Abstract Details

Activity Number: 316
Type: Invited
Date/Time: Tuesday, August 2, 2011 : 10:30 AM to 12:20 PM
Sponsor: General Methodology
Abstract - #300230
Title: Practical Implementations of Decision-Theoretic Multiple Inferences
Author(s): Peter Westfall*+ and Russ Wolfinger and Randy Tobias and Ananda Managa
Companies: Texas Tech University and SAS Institute Inc. and SAS Institute Inc. and Sam Houston State University
Address: Department of Information Systems and Quantitative, Lubbock, TX, 79409-2101,
Keywords: Multiple Comparisons ; Multiple Testing ; Familywise Error Rate ; False Discovery Rate ; Bayesian Methods ; Scale up
Abstract:

With so many multiple comparisons methods to choose from, practitioners face a bewildering array of choices. And they just want to know, "which is the best method?" Decision theoretic methods offer an answer to the question; and modern computing allows simple, Monte Carlo-based solutions. The problem is then determining the loss functions. The question of "scientific loss" due to Type I and Type II errors is considered carefully in the context of genomic data, loss functions are carefully developed, and recommendations are given. The methods are implemented using SAS software.


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