JSM 2011 Online Program

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Abstract Details

Activity Number: 100
Type: Invited
Date/Time: Monday, August 1, 2011 : 8:30 AM to 10:20 AM
Sponsor: Section on Bayesian Statistical Science
Abstract - #300210
Title: Bayesian Methods for Causal Inference on Mediators with Application to Weight Management Clinical Trials
Author(s): Michael Daniels*+ and Jason Roy and Chanmin Kim and Joseph Hogan and Michael Perri
Companies: University of Florida and University of Pennsylvania and University of Florida and Brown University and University of Florida
Address: Department of Statistics, Gainesville, FL, 32611, USA
Keywords: Mediation ; Sensitivity analysis
Abstract:

We propose a nonparametric Bayesian approach to estimate the natural direct and indirect effects of a mediator in the setting of a continuous mediator and a binary response. Several conditional independence assumptions are introduced (with corresponding sensitivity parameters) to make these effects identifiable from the observed data. This approach is used to assess mediation in a recent weight management clinical trial.


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