JSM 2011 Online Program

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Abstract Details

Activity Number: 378
Type: Invited
Date/Time: Tuesday, August 2, 2011 : 2:00 PM to 3:50 PM
Sponsor: Biometrics Section
Abstract - #300203
Title: Using Phylogenetic Relationships to Infer Gene Functional Groups
Author(s): Jun Liu*+ and Yang Li and Roee Gutman
Companies: Harvard University and Shanghai JiaoTong University and Harvard University
Address: Department of Statistics, Cambridge, MA, 02138,
Keywords: Phylogeny ; Markov chain Monte Carlo
Abstract:

When a set of genes (proteins) appear and disappear simultaneously from many different species, it suggests that these genes are likely functionally related. We developed novel method to infer such functional relationship among the genes by directly modeling the phylogenetic relationships among the species. Simulation studies and experimental validations show that the method is superior to other heuristic approaches.


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