This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
|CE_23T||Wed, 8/4/2010, 8:00 AM - 9:45 AM||CC-8 (East)|
|Meta-Analysis: Concepts and Applications — Continuing Education CTW|
|ASA , Biostat, Inc.|
|Instructor(s): Michael Borenstein, Biostat, Inc., Hannah Rothstein|
|Meta-analysis is a set of statistical procedures to synthesize data from multiple studies. When the studies share a common effect size the meta-analysis yields a more precise estimate of that effect than any single study. When the effect size varies from one study to the next, meta-analysis may be used to explain this variation. Meta-analyses are used to inform policy, to obtain approval for drugs, and to design new research. They also play a key role in grant applications and publications. We will explain the concept of meta-analysis and show how to compute treatment effects, compute a combined effect, assess heterogeneity, and explain variation in treatment effects across studies. We will discuss the difference between fixed and random effects models, and will address common criticisms of meta-analysis such as the issue of combining different kinds of data "Apples and oranges", and conflicts between meta-analyses and clinical trials. We will demonstrate Comprehensive Meta Analysis Version 2 (Borenstein, Hedges, Higgins, Rothstein), a program developed with funding from the NIH. The course is intended for people who perform or interpret meta-analyses. Attendees should have some familiarity with meta- analysis, but the course will cover the basics before moving on to more advanced topics.|