This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Abstract - #309256
Title: WITHDRAWN - Markov Chain Likelihood in Long Binary Sequence Data
Author(s): Jianping Sun and Bruce G. Lindsay
Keywords: Statistical Genetics ; Markov Chain Likelihood ; Ancestral Distribution

The primary goal of this talk is the analysis of long sequence data generated in biology, such as SNP data. Suppose we observe n current descendant sequences of length L, one interesting question is how to estimate the unknown ancestral distribution considering realistic biology complexities such as mutation and recombination. We have developed a statistical model with both mutation and recombination to estimate the ancestral distribution. However, though we can write out the full likelihood for ancestral distribution explicitly, there is an enormous computation challenge due to an enormous number of recombination possibilities, which grows exponentially in sequence length. Therefore, we apply Markov Chain likelihood as an approximation to solve the problem. In this talk, we'll introduce our developed statistical model and investigate the performance of Markov Chain likelihood method.

The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2010 program

2010 JSM Online Program Home

For information, contact or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.