This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 416
Type: Contributed
Date/Time: Tuesday, August 3, 2010 : 2:00 PM to 3:50 PM
Sponsor: Section on Nonparametric Statistics
Abstract - #308677
Title: Inference for Treatment Efficacy on Survival Probability in Randomized Clinical Trials with Noncompliance
Author(s): Ying Zhou*+
Companies: University of California, Los Angeles
Address: 3780 Keystone Ave, Apt 412, Los Angeles, CA, 90034,
Keywords: Causual inference ; Semiparametric estimation ; Right censoring ; All-or-nothing compliance ; Asymptotic normality ; Suvival analysis
Abstract:

We propose a semiparametric inference procedure for assessing treatment efficacy in terms of the difference in survival probabilities in randomized clinical trials with all-or-nothing compliance. An iterative procedure is derived for calculating the semiparametric maximum likelihood estimators. Large sample properties and inference are developed. We evaluate our method by simulation studies, and illustrate it using the Multicenter Selective Lymphadenectomy Trial I, a randomized clinical trial for melanoma.


The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2010 program




2010 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.