This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 360
Type: Contributed
Date/Time: Tuesday, August 3, 2010 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #308483
Title: Quality Control for Whole-Genome DASL Assay
Author(s): Jisuk Jo*+ and Insuk Sohn and Sin-Ho Jung and Soonmyung Paik
Companies: Samsung Medical Center and Samsung Medical Center and Duke University and Samsung Medical Center
Address: , , ,
Keywords: Quality control ; WG-DASL ; Microarray ; Preprocessing

Quality control (QC) is an important step in microarray gene expression study when determining the reliability for performed experiment. Additionally, we would obtain superb analytic results when the results are derived from the microarray for an effective QC outcome. In particular, QC is a crucial issue given that the RNA that is extracted from a FFPE tissue sample, made up of immense archives of pathologically well-characterized clinical samples from randomized trials, might result in degradation. Through the Whole-Genome DASL assay, which has an advantage in microarray gene expression study using RNA from FFPE tissues, we will demonstrate the QC process which resulted in the reliable outcome of WG-DASL assay. In order to do so, we used GenomeStudio and R program, which provides the raw data and QC results, respectively, to cause the WG-DASL assay to the gastric cancer patient.

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