This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Abstract - #308377
Title: WITHDRAWN: Bayesian Methods in Combination Drug Studies: A Performance Analysis
Author(s): Peiqi Zhai
Companies:
Address:
Keywords: Combination Index, Bayesian, Logistic Regression, Power, Error.
Abstract:

One prevalent goal within clinical trials is to determine whether or not two drugs interact when applied in combination. Holt, Stamey, Seaman, and Young (2008) applied Bayesian analysis and proposed a min test for drug interaction, assuming that non-interaction is modeled by statistical independence. The methods discussed by Holt, Stamey, Seaman and Young were specifically targeted to fixed-dose combination studies that involve binary response data. The authors provided a limited comparison of the Type I error and power of the two procedures using Monte Carlo simulation. This thesis extends the study of Holt et al. (2008) using different prior structures for the min test to study the performance of Bayesian analysis in drug studies.


The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.

Back to the full JSM 2010 program




2010 JSM Online Program Home

For information, contact jsm@amstat.org or phone (888) 231-3473.

If you have questions about the Continuing Education program, please contact the Education Department.