This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
|
Activity Number:
|
452
|
|
Type:
|
Topic Contributed
|
|
Date/Time:
|
Wednesday, August 4, 2010 : 8:30 AM to 10:20 AM
|
|
Sponsor:
|
Biometrics Section
|
| Abstract - #307995 |
|
Title:
|
A Genomewide Association Study for Determinants of Hyperlipidemia in Korean Population via Beyond-Single-SNP Analysis
|
|
Author(s):
|
Taesung Park*+ and Eunjin Lee and Kyunga Kim and Seungyeoun Lee
|
|
Companies:
|
Seoul National University and Seoul National University and Seoul National University and Sejong University
|
|
Address:
|
56-1 Shillim-Dong Kwanak-Gu, Seoul, 151-747, South Korea
|
|
Keywords:
|
GWAS ;
association study ;
gene-gene interaction ;
multipel genes
|
|
Abstract:
|
We conducted Genome-Wide Association Study of lipid-related traits such as Total cholesterol, High density lipoprotein cholesterol, Low density lipoprotein cholesterol and Triglycerides with 327,872 SNP markers to identify genotype-phenotype association for Korean population. Our study included 8800 participants from recruitment areas: Ansan and Ansung which are urban and rural areas in Korea, respectively. We first performed separate analysis for each recruitment areas and then performed combined analysis. We showed a simple addition of area into the regression model is not enough for adjustment. We discussed several methods for combined analysis and compare their pros and cons.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.