This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 609
Type: Topic Contributed
Date/Time: Thursday, August 5, 2010 : 8:30 AM to 10:20 AM
Sponsor: Biometrics Section
Abstract - #307917
Title: Discovery and Validation of Gene Coexpression Groups Affecting a Trait
Author(s): Cheng Cheng*+
Companies: St. Jude Children's Research Hospital
Address: , , ,
Keywords: gene coexpression ; gene expression ; trait ; phenotype ; validation

A complex human trait is most likely affected by a group (network) of inter-regulated genes. This research concerns with the discovery of such gene groups through a trait-driven dimension reduction approach using large datasets generated by genome-wide gene expression microarrays, and the inference for validation of the findings on an external, independent dataset.

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