This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
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Activity Number:
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285
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Type:
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Topic Contributed
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Date/Time:
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Tuesday, August 3, 2010 : 8:30 AM to 10:20 AM
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Sponsor:
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Biometrics Section
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| Abstract - #307439 |
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Title:
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Quantifying Output from Protein Mass Spectrometry Experiments: An Overview
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Author(s):
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Tim Randolph*+
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Companies:
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Fred Hutchinson Cancer Research Center
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Address:
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1100 Fairview Ave. N., M2-B500, Seattle, WA, 98109,
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Keywords:
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Mass spectrometry ;
LC-MS ;
Proteomics ;
Spectral counting
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Abstract:
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As an introduction to this special session on Statistical and Computational Methods for Proteomics we survey some of the issues related to quantification in liquid-chromoatography mass-spectrometry (LC-MS) experiments. These data share some of the same issues as gene expression array data (e.g., high dimensionality and normalization), but they arise from a more complicated data-generation process and so a variety of aspects need to be understood prior to statistical analysis. We describe various types of output from LC-MS/MS experiments and provide some empirical observations about statistical models/methods used for quantifying and analyzing these data.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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