This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 571
Type: Topic Contributed
Date/Time: Wednesday, August 4, 2010 : 2:00 PM to 3:50 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #307298
Title: Performance of Prediction Measures in a Survival Setting
Author(s): Nina P. Paynter*+ and Linda M. Peelen and Nancy Cook
Companies: Brigham and Women's Hospital and Julius Center for Health Sciences and Primary Care UMC Utrecht and Brigham and Women's Hospital
Address: 900 Commonwealth Ave, Boston, MA, 02215,
Keywords: prediction ; survival ; time-to-event data ; evaluation ; simulation
Abstract:

Prediction models are often generated using time-to-event data, but many prediction measures, especially those conditional on final outcome status, are evaluated at a fixed time. We will examine measures of discrimination, calibration, and reclassification which account for survival data. We will present the results of a series of simulations to explore the type I error, power, and magnitude of effect for the comparison of models with and without a new added predictor under a range of conditions. We will also present the effects of various methods of handling censoring, including omitting censored subjects and counting the censored subjects as non-events, which have not previously been examined for reclassification methods.


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