This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 227
Type: Topic Contributed
Date/Time: Monday, August 2, 2010 : 2:00 PM to 3:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #307121
Title: Sample Size Estimates for Correlated Data in a Device Trial
Author(s): Xiaolong Shih*+
Companies: Boston Scientific Corporation
Address: 4100 Hamline Ave North, St Paul, MN, 55112,
Keywords: repeated measurement ; correlated data ; linear interpolation ; sample size estimate ; simulation
Abstract:

In a medical device trial of Drug Eluting Stents (DES), there are multiple experimental units within each patient for a certain portion of the study population. This can pose challenge to the conventional statistical methods in the sample size estimate. An idea of sample size calculation by interpolating multiple methods is proposed. Simulation examples will be presented to demonstrate the validity of this new computational method.


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