This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 61
Type: Topic Contributed
Date/Time: Sunday, August 1, 2010 : 4:00 PM to 5:50 PM
Sponsor: Biopharmaceutical Section
Abstract - #307076
Title: Assessment of Exact Patient Year Method for Clinical Outcome in Drug-Eluting Stent Trials
Author(s): Peter Lam*+ and Heather Bai and Jian Huang and Hong Wang
Companies: Boston Scientific Corporation and Boston Scientific Corporation and Boston Scientific Corporation and Boston Scientific Corporation
Address: 100 Boston Scientific Corporation, Marlborough, MA, 01752, United States
Keywords: exact patient year ; drug-eluting stent ; life table ; statistical test

The patient year method has been widely used in epidemiology. Recently the approach was applied to drug eluting stent trials and several papers were published in journal of American college of cardiology1 (JACC) and circulation: cardiovascular intenvention2 (AHA). We will use the exact patient year approach to assess clinical outcomes in a drug eluting stent trial and compare the annualized hazard rate with life table approach. The drug eluting stent trial data will be used to demonstrate the difference of the two approaches. A proposed statistical testing methodology will be explored for each method.

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