This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
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Activity Number:
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256
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Type:
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Contributed
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Date/Time:
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Monday, August 2, 2010 : 2:00 PM to 3:50 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #306981 |
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Title:
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Correcting an Incorrect Statistical Practice in Pharmacokinetics and Related Fields
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Author(s):
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Jingyuan Wang*+
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Companies:
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Millennium Pharmaceuticals, Inc.
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Address:
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, Cambridge, MA, 02139,
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Keywords:
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pharmacokinetics ;
renew process ;
compartment model
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Abstract:
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Mean residence time(MRT) is a common parameter used in pharmacokinetics to describe the amount of time a drug stays in the body. The current practice is to use a probability distribution proportional to drug concentration to estimate MRT. This practice is mathematically incorrect. Correct methods for both one-compartment and two-compartment models will be presented. The new methods are rigorously derived using some simple differential equations and a little bit of results from renew process.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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