This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
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Activity Number:
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498
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Type:
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Topic Contributed
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Date/Time:
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Wednesday, August 4, 2010 : 10:30 AM to 12:20 PM
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Sponsor:
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Biopharmaceutical Section
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| Abstract - #306796 |
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Title:
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Covariate-Adjusted Response-Adaptive Randomization Design with Survival Responses
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Author(s):
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Hongjian Zhu* and Feifang Hu+
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Companies:
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University of Virginia and University of Virginia
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Address:
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P. O. BOX 400135, CHARLOTTESVILLE, VA, 22903,
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Keywords:
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response-adaptive randomization ;
covariate ;
survival data ;
cox proportional hazards model
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Abstract:
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Response-adaptive randomization procedures have numerous merits in terms of ethics and optimization. However, it is unclear how to use response-adaptive randomization procedure for survival responses when covariate information is available. In this talk, we proposed a framework for covariate-adjusted response-adaptive randomization design combined with Cox proportional hazards model. The asymptotic properties of this design were also obtained. In addition, we analyzed a specific allocation scheme from this framework. Some numerical studies were performed and analyzed.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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