This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 343
Type: Contributed
Date/Time: Tuesday, August 3, 2010 : 10:30 AM to 12:20 PM
Sponsor: ENAR
Abstract - #306392
Title: A Bivariate Mover-Stayer Model for Interval-Censored Recurrent Event Data: Application to Joint Damage in Rheumatology
Author(s): Rinku Sutradhar*+
Companies: Institute for Clinical Evaluative Sciences
Address: G Wing - 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada
Keywords: Heterogeneity ; Association ; Inetrval censoring ; Joint damage ; Non-susceptible fraction

Interval-censored recurrent event data can exhibit considerable between subject heterogeneity in the event rate, and frequently there is a proportion of individuals experiencing no events. We consider a likelihood based analysis of bivariate interval-censored recurrent event data in which a random effect is used to accommodate heterogeneity in the rate of events, and bivariate mover-stayer indicators are introduced to accommodate a nonsusceptible sub-population for each type of event. The motivating data arises from a study on joint damage in patients with psoriatic arthritis. For every patient, each joint is assessed for damage using both clinical and radiological measures over the duration of follow-up. The proposed model facilitates estimation of the joint distribution of the mover-stayer indicators for both clinical and radiological joint damage.

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