This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 276
Type: Invited
Date/Time: Tuesday, August 3, 2010 : 8:30 AM to 10:20 AM
Sponsor: SSC
Abstract - #306325
Title: Issues in the Meta-Analysis of Observational Data
Author(s): George A. Wells*+
Companies: University of Ottawa Heart Institute
Address: Room H1281, 40 Ruskin Street, Ottawa, ON, K1Y 4W7,
Keywords:
Abstract:

Non-randomized studies (NRS) do not use randomization for allocating to comparison groups. This includes studies where allocation occurs in the course of usual treatment decisions or peoples' choices. NRS include cohort, case-control, controlled before-and-after, interrupted-time-series studies and controlled trials with inappropriate randomization strategies. The Meta-analysis Of Observational Studies in Epidemiology (MOOSE) and QUality Of Reporting Of Meta-analyses (QUOROM) guidelines provide a foundation for integrating data from observational studies. For NRS reviews, the following will be considered: inclusion criteria, searching, selecting and collecting data, assessing quality and synthesis of data. Among the items to consider when integrating analysis from NRS are methods of handling missing data. Potential directions for handling missing data will be discussed.


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