This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 493
Type: Invited
Date/Time: Wednesday, August 4, 2010 : 10:30 AM to 12:20 PM
Sponsor: International Chinese Statistical Association
Abstract - #306208
Title: Exploring the 1000 Genomes Project with Bioconductor
Author(s): Vincent James Carey*+
Companies: Harvard Medical School
Address: 181 Longwood Ave, Boston, MA, 02115,
Keywords: genetics ; next-generation sequencing ; statistical computing

The 1000 genomes project ( aims to create a "deep catalog of human genetic variation", with extensive use of next-generation sequencing technologies. Important scientific agendas are already proceeding on the basis of this project, including the creation of dense SNP imputation schemes based on variants identified in deep sequencing of HapMap samples. I describe how tools developed in the Bioconductor project ( can be used to interactively acquire and analyze deep sequencing results provided through 1000 genomes, with particular attention to capacities for sensitivity analysis and assessment of reproducibility of published research results.

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