This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
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Activity Number:
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144
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Type:
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Invited
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Date/Time:
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Monday, August 2, 2010 : 10:30 AM to 12:20 PM
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Sponsor:
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International Indian Statistical Association
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| Abstract - #306201 |
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Title:
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Statistical Analysis of Somatic Changes in Cancer Genomics
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Author(s):
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Giovanni Parmigiani*+
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Companies:
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Harvard University
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Address:
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44 Binney Street, Boston, MD, 02115,
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Keywords:
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cancer ;
genomics ;
gene sets ;
fdr ;
sample size
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Abstract:
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Cancer genome projects collect high resolution genome-wide information on genetic changes that are found in cancer but not in originating cells. These include somatic mutations, copy number changes, methylation, expression and more. Computational methodologies can organize these rich but hard to interpret set of results into a cohesive set of genetically altered core pathways and regulatory processes. They can also provide guidance for a variety of additional etiologic and therapeutic investigations, and for the design of future studies. In this presentation I will survey methodological tools from these studies, with a focus on recent advances and open issues.
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The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
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