This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.

Abstract Details

Activity Number: 51
Type: Invited
Date/Time: Sunday, August 1, 2010 : 4:00 PM to 5:50 PM
Sponsor: IMS
Abstract - #306159
Title: Semiparametric Additive Mixed Effect Model for Multivariate Failure Time Data
Author(s): Jianwen Cai*+
Companies: The University of North Carolina at Chapel Hill
Address: Department of Biostatistics, CB #7420, Chapel Hill, NC, 27599-7420,
Keywords: multivariate failure time ; mixed effect ; estimating equations
Abstract:

We propose a semiparametric additive mixed effect model for modelling multivariate failure time data. A cluster-specific random effect is introduced to the additive intensity model to account for the dependence of the correlated failure times. We construct an estimating equation for parameter estimation. The asymptotic distributions of the proposed estimators are derived. Simulation studies demonstrate that the proposed inference procedure performs well in realistic settings. We apply the proposed method to analyze data from a medical study.


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