This is the program for the 2010 Joint Statistical Meetings in Vancouver, British Columbia.
Abstract Details
|
Activity Number:
|
271
|
|
Type:
|
Invited
|
|
Date/Time:
|
Tuesday, August 3, 2010 : 8:30 AM to 10:20 AM
|
|
Sponsor:
|
ENAR
|
| Abstract - #305933 |
|
Title:
|
An Efficient Method for Estimating Chromosome Copy Number of Variations and Its Theoretical Properties
|
|
Author(s):
|
Yue Selena Niu*+ and Heping Zhang
|
|
Companies:
|
The University of Arizona and Yale University
|
|
Address:
|
, , 85721,
|
|
Keywords:
|
copy number variation ;
change-point ;
bandwidth ;
kernel ;
Comparative genomic hybridization
|
|
Abstract:
|
DNA copy number is the number of copies of DNA at a region of a genome. A lot of complex diseases involve alterations in DNA copy number, such as cancer progression. Many statistical methods have been proposed and applied in analysis of detecting chromosome copy number variations. However, few have studied the theoretical properties of those methods or used potentially important theory to improve the methods. In this talk, we proposed a two-step method and investigated its asymptotic properties. Simulations examples and real data analysis are investigated.
|
The address information is for the authors that have a + after their name.
Authors who are presenting talks have a * after their name.
Back to the full JSM 2010 program
|
2010 JSM Online Program Home
For information, contact jsm@amstat.org or phone (888) 231-3473.
If you have questions about the Continuing Education program, please contact the Education Department.