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This is the preliminary program for the 2009 Joint Statistical
Meetings in Washington, DC.
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The views expressed here are those of the individual authors and not necessarily those of the ASA or its board, officers, or staff. Back to main JSM 2009 Program page |
= Applied Session,
= Theme Session,
= Presenter| CE_38T | Wed, 8/5/09, 1:00 PM - 2:45 PM | RH-Meeting Rooms 12, 13, 14 |
| Group Sequential Analysis Using SAS Software - Continuing Education - CTW | ||
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ASA |
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| Instructor(s): Yang Yuan, SAS Institute Inc. | ||
| A group sequential trial provides for interim analyses before completion of a clinical trial. These group sequential methods can help prevent the unnecessary exposure of patients to an unsafe new drug, or alternatively, to a placebo treatment if a new drug shows tremendous promise. This workshop reviews basic concepts of group sequential analysis and introduces two SAS/STAT procedures: SEQDESIGN and SEQTEST. The SEQDESIGN procedure creates group sequential designs by computing boundary values with a variety of methods, including the O'Brien-Fleming, Whitehead, and error spending methods; it also computes required sample sizes. The SEQTEST procedure compares the test statistic with the corresponding boundary values at each stage so the trial can be stopped to reject or accept the hypothesis. It also computes parameter estimates, confidence limits, and a p-value after the trial stops. Numerous examples will illustrate the capabilities of the software. Attendees should have experience with hypothesis testing and familiarity with SAS procedures such as REG and LOGISTIC. | ||
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JSM 2009
For information, contact jsm@amstat.org
or phone (888) 231-3473. If you have questions about the Continuing Education program,
please contact the Education Department. |