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Activity Number: 315
Type: Contributed
Date/Time: Tuesday, August 4, 2009 : 10:30 AM to 12:20 PM
Sponsor: Section on Statistics in Epidemiology
Abstract - #303228
Title: Interval Estimation of Risk Difference for Clustered Data
Author(s): Tasneem Zaihra*+ and Sudhir R. Paul
Companies: University of Windsor and University of Windsor
Address: 270 Patricia Road, Windsor, ON, N9B 3B9, Canada
Keywords: Clustered binary data ; Epidemiological Index ; Risk difference ; Intracluster-correlation
Abstract:

Risk difference is one of the most popular epidemiological index used to compare the probability of developing a disease for individuals in an intervention group with that in a control group. There are varying cluster sizes in each group and the binary responses within each clusters are correlated. In our presentation we introduce 2 very simple methods under the cluster sampling scenario. One method is based on variance of a ratio estimator and the other is based on a sandwich estimator of the variance using the generalized estimating equations approach. These two methods are then compared, by simulation, in terms coverage probability, coverage length, symmetry and bias with other 4 methods for confidence interval construction discussed by Lui (Statistical Estimation of Epidemiological Risk, 2004).The method based on an estimate of the variance of a ratio estimator performs best overall.


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