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Activity Number:
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163
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Type:
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Contributed
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Date/Time:
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Monday, August 3, 2009 : 10:30 AM to 12:20 PM
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Sponsor:
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Section for Statistical Programmers and Analysts
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| Abstract - #305868 |
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Title:
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Open Source Adaptive Design Software in a Regulated Environment: A Case Study
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Author(s):
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Keaven Anderson*+
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Companies:
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Merck & Co., Inc.
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Address:
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, Upper Gwynedd, PA, 19454,
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Keywords:
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Group sequential design ; software
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Abstract:
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We consider the gsDesign R package for group sequential design that provides computational tools enabling design optimization, substantial customization capability and application to adaptive design. While many standard 2-arm group sequential designs are easily dealt with using off-the-shelf commercial software, custom reports or variations on what is available in a package are often desired. R provides a great platform for simply customizing upon a well-conceived and validated toolset. gsDesign is a collaboration between a researcher and software developer that may provide a model for areas like adaptive design where customization is often desirable. A toolset that conforms to good coding and documentation practices, has built-in checking to ensure updates do not introduce errors, and is available in an open, collaborative environment is a powerful enabler of innovation.
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- The address information is for the authors that have a + after their name.
- Authors who are presenting talks have a * after their name.
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