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Activity Number: 606
Type: Contributed
Date/Time: Thursday, August 6, 2009 : 10:30 AM to 12:20 PM
Sponsor: Biometrics Section
Abstract - #305638
Title: Time-Dependent ROC Methods and Concordance Measures
Author(s): Norberto Pantoja-Galicia*+ and Rebecca Betensky
Companies: Harvard School of Public Health and Harvard School of Public Health
Address: , , ,
Keywords: Concordance measure ; Kendall's tau ; Time dependent ROC methods ; U-statistics ; c-index
Abstract:

We show the connection between different definitions of time dependent sensitivity and specificity in terms of concordance measures. We explore the relationship between such measures and their corresponding area under the ROC curve. An estimation procedure for a concordance measure is proposed and its asymptotic variance is derived. We compare our estimated variance with other variance estimation procedures presented in the literature. An application in the context of Alzheimer's disease is presented.

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